Diagnosis Hemofilia

Hemophilia is a hereditaty coagulation disorder which is inherited as an X-link recessive trait. Disorder happens in the intrinsic hemostasis pathway, in which there is a deficiency or defect of coagulation factor VIII (Hemophilia A) or IX (Hemophilia B). Hemophilia is comnron in male, though occurrence in female has also been reported. Female usually are carries. Immunologically, there are several variants of hemophilia. Diagnosis of hemophilia can be made by carrier detection, clinical manfestation, and laboratoty tests. This article presents the diagnostic aspects of hemophilia A and B from physical to genetic examination. As references of hemophilia are still are, this article is expected to be useful in improving our knowledge so that this di sease can be anticipated earlier and maaged properly.